| Date | Home | Away | Result |
|---|---|---|---|
| 12/19/25 1:45 PM | Sporting Charleroi | KRC Genk | 2-2 |
| 12/20/25 9:00 AM | FCV Dender EH | Standard Liège | 0-1 |
| 12/20/25 11:15 AM | KVC Westerlo | RAAL La Louviere | 2-1 |
| 12/20/25 1:45 PM | Royale Union Saint-Gilloise | SV Zulte-Waregem | 2-0 |
| 12/21/25 6:30 AM | Club Brugge | KAA Gent | 2-1 |
| 12/21/25 9:00 AM | Sint-Truidense VV | KV Mechelen | 1-0 |
| 12/21/25 11:30 AM | Royal Antwerp FC | RSC Anderlecht | 2-2 |
| 12/21/25 12:15 PM | OH Leuven | KSV Cercle Brügge | 0-2 |